Publications

Rapid Point-of-Care Identification of Aspergillus Species in Microbial Keratitis (2023)

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Location of CD39+ T cell subpopulations within tumors predict differential outcomes in non-small cell lung cancer (2023)

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Selective plane illumination optical endomicroscopy with polymer imaging fibers (2023)

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Specific in situ immuno-imaging of pulmonary-resident memory lymphocytes in human lungs. (2023)

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Data-Driven Steering of Concentric Tube Robots in Unknown Environments via Dynamic Mode Decomposition (2023)

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Environmentally sensitive photosensitizers enable targeted photodynamic ablation of Gram-positive antibiotic resistant bacteria (2023)

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FluoroPi Device With SmartProbes: A Frugal Point-of-Care System for Fluorescent Detection of Bacteria From a Pre-Clinical Model of Microbial Keratitis (2023)

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Computational Fluorescence Suppression in Shifted Excitation Raman Spectroscopy (2023).

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Fluorogenic Granzyme A Substrates Enable Real-Time Imaging of Adaptive Immune Cell Activity (2023)

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Phase 2 randomised placebo-controlled trial of spironolactone and dexamethasone versus dexamethasone in COVID-19 hospitalised patients in Delhi (2023)

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Specific in situ immuno-imaging of pulmonary-resident memory lymphocytes in human lungs (2023)

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Simultaneous Spectral Temporal Modelling for a Time-Resolved Fluorescence Emission Spectrum (2023)

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A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies (2022)

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An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis (DEFINE): A Phase Ib/IIa Randomised Controlled Trial (2022)

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Deep Learning-Assisted Co-registration of Full-Spectral Autofluorescence Lifetime Microscopic Images with H&E-Stained Histology Images (2022)

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Diagnosing ventilator-associated pneumonia (VAP) in UK NHS ICUs: the perceived value and role of a novel optical technology (2022)

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Fast and robust single-exponential decay recovery from noisy fluorescence lifetime imaging (2022)

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Fibroblast Activation Protein specific optical imaging in Non-Small Cell Lung Cancer (2022).

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High resolution TCSPC imaging of diffuse light with a one-dimensional SPAD array scanning system (2022).

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Optimizing the implementation of lung cancer screening in Scotland: Focus group participant perspectives in the LUNGSCOT study (2022).

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Phototherapeutic Induction of Immunogenic Cell Death and CD8+ T Cell-Granzyme B Mediated Cytolysis in Human Lung Cancer Cells and Organoids (2022)

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Randomised Controlled Trial of Intravenous Nafamostat Mesylate in COVID pneumonitis: Phase 1b/2a Experimental Study to Investigate Safety, Pharmacokinetics and Pharmacodynamics (2022)

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Tri-mode optical biopsy probe with fluorescence endomicroscopy, Raman spectroscopy, and time-resolved fluorescence spectroscopy (2022).

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Understanding patient barriers and facilitators to uptake of lung screening using low dose computed tomography: a mixed methods scoping review of the current literature (2022).

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A Functional Chemiluminescent Probe for in vivo Imaging of Natural Killer Cell Activity against Tumours (2021)

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Activated neutrophil fluorescent imaging technique for human lungs (2021).

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Design and Modelling of a Continuum Robot for Distal Lung Sampling in Mechanically Ventilated Patients in Critical Care (2021)

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Full spectrum fluorescence lifetime imaging with 0.5 nm spectral and 50 ps temporal resolution (2021)

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Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism (2021)

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Multi-Scale Aggregated-Dilation Network for ex-vivo Lung Cancer Detection with Fluorescence Lifetime Imaging Endomicroscopy (2021).

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Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections (2021)

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Solitary pulmonary nodule imaging approaches and the role of optical fibre-based technologies (2021).

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T cells drive negative feedback mechanisms in Cancer Associated Fibroblasts, promoting expression of co-inhibitory ligands, CD73 and IL-27 in non-small cell lung cancer (2021)

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Time-resolved spectral-domain optical coherence tomography with CMOS SPAD sensors (2021)

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Tissue proteomic analysis identifies mechanisms and stages of immunopathology in fatal COVID-19 (2021)

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A matrix metalloproteinase activation probe for painting human tumours (2020).

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Demonstrating the Use of Optical Fibres in Biomedical Sensing: A Collaborative Approach for Engagement and Education (2020)

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Deep Learning in ex-vivo Lung Cancer Discrimination using Fluorescence Lifetime Endomicroscopic Images (2020).

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Exploratory use of fluorescent SmartProbes for the rapid detection of microbial isolates causing corneal ulcer (2020).

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Frugal filtering optical lenses for point-of-care diagnostics (2020)

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Molecular detection of Gram-positive bacteria in the human lung through an optical fiber–based endoscope (2020).

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Polymyxin-based photosensitizer for the potent and selective killing of Gram-negative bacteria (2020).

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The role of fungi in fungal keratitis (2020)

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Time-Resolved Spectroscopy of Fluorescence Quenching in Optical Fibre-Based pH Sensors (2020)

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Ultrafast-laser-ablation-assisted spatially selective attachment of fluorescent sensors onto optical fibers (2020)

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A Fluorescent Activatable AND-Gate Chemokine CCL2 Enables In Vivo Detection of Metastasis-Associated Macrophages (2019)

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Enhanced avidity from a multivalent fluorescent antimicrobial peptide enables pathogen detection in a human lung model (2019).

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Fibre-based spectral ratio endomicroscopy for contrast enhancement of bacterial imaging and pulmonary autofluorescence (2019)

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Genetic variation and potential for genetic improvement of cuticle deposition on chicken eggs (2019).

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Cerebral Concussion Primes the Lungs for Subsequent Neutrophil-Mediated Injury (2018)

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Development of an Alveolar Transbronchial Catheter for Concurrent Fiber Optics-Based Imaging and Fluid Delivery (2018).

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Early arriving photon imaging for locating optical endomicroscopy fibres and medical devices (2018).

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High fidelity fibre-based physiological sensing deep in tissue (2018)

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Low-cost high sensitivity pulsed endomicroscopy to visualize tricolor optical signatures (2018)

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Super-silent FRET sensor enables live cell imaging and flow cytometric stratification of intracellular serine protease activity in neutrophils (2018).

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Ballistic and snake photon imaging for locating optical endomicroscopy fibres (2017).

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Chemical Modulation of in Vivo Macrophage Function with Subpopulation-Specific Fluorescent Prodrug Conjugates (2017)

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Highly selective and rapidly activatable fluorogenic Thrombin sensors and application in human lung tissue (2017)

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Optical Screening of Novel Bacteria-specific Probes on Ex Vivo Human Lung Tissue by Confocal Laser Endomicroscopy (2017).

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Novel role for endogenous mitochondrial formylated peptide-driven formyl peptide receptor 1 signalling in acute respiratory distress syndrome (2017)

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pH sensing through a single optical fibre using SERS and CMOS SPAD line arrays (2017)

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Time-resolved spectroscopy at 19,000 lines per second using a CMOS SPAD line array enables advanced biophotonics applications (2017).

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Assessing the utility of autofluorescence-based pulmonary optical endomicroscopy to predict the malignant potential of solitary pulmonary nodules in humans (2016).

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Endoscopic sensing of alveolar pH (2016).

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Two-color widefield fluorescence microendoscopy enables multiplexed molecular imaging in the alveolar space of human lung tissue (2016).

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A labelled-ubiquicidin antimicrobial peptide for immediate in situ optical detection of live bacteria in human alveolar lung tissue (2015).

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Optical molecular imaging of lysyl oxidase activity–detection of active fibrogenesis in human lung tissue (2015).

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