Polymyxin-based photosensitizer for the potent and selective killing of Gram-negative bacteria (2020).

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Ucuncu M, Mills B, Duncan S, Staderini M, Dhaliwal K, Bradley M.


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Here we report the synthesis of a novel methylene blue-polymyxin conjugate and demonstrate its light-mediated killing of Gram-negative bacteria on skin models of infection demonstrating a 108 decrease in bacterial colony-forming units.


Posted on

June 5, 2023

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