Publications

 

Computational Fluorescence Suppression in Shifted Excitation Raman Spectroscopy (2023).
Jenkins N, Ehrlich K, Kufcsak A, Yerolatsitis S, Fernandes S, Young I, Hamilton K, Wood HA, Quinn T, Young V, Akram AR, Stone JM, Thomson RR, Finlayson K, Dhaliwal K, Seth S. | PubMed 

 

Simultaneous Spectral Temporal Modelling for a Time-Resolved Fluorescence Emission Spectrum (2023)
Adams AC, Kufcsak A, Ehrlich K, Dhaliwal K, Seth S. | PubMed 

 

Tri-mode optical biopsy probe with fluorescence endomicroscopy, Raman spectroscopy, and time-resolved fluorescence spectroscopy (2022). 

Wood HA, Ehrlich K, Yerolatsitis S, Kufcsák A, Quinn TM, Fernandes S, Norberg D, Jenkins NC, Young V, Young I, Hamilton K, Seth S, Akram AR,Thomson RR, Finlayson K, Dhaliwal K, Stone JM. | PubMed

 

High resolution TCSPC imaging of diffuse light with a one-dimensional SPAD array scanning system (2022).

E P McShane, H K Chandrasekharan, A Kufcsák, N Finlayson, A T Erdogan, R K Henderson, K Dhaliwal, R R Thomson, M G Tanner | PubMed 

 

An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis (DEFINE): A Phase Ib/IIa Randomised Controlled Trial (2022).

Gaughan EE, Quinn TM, Mills A, Bruce A M, Antonelli J, Mackinnon A, Aslanis V, Li F, O’connor R, Boz C, Mills R, Emanuel P, Burgess M, Rinaldi G, Valanciute A, Mills B, Scholefield E, Hardisty G, Gwyer Findlay E, Parker R A, Norrie J, Dear JW, Akram AR, Koch O, Templeton K, Dockrell DH, Walsh TS, Partridge S, Humphries D, Wang-Jairaj J, Slack RJ, Schambye H, Phung D, Gravelle L, Lindmark B, Shankar-Hari M, Hirani N, Sethi T, Dhaliwal K. | PubMed

 

Randomised Controlled Trial of Intravenous Nafamostat Mesylate in COVID pneumonitis: Phase 1b/2a Experimental Study to Investigate Safety, Pharmacokinetics and Pharmacodynamics (2022).

Quinn T, Gaughan E E, Bruce A, Antonelli J, O’Connor R A, Li F, McNamara S, Koch O, Mackintosh C, Dockrell D, Walsh T, Blyth K G, Church C, Schwarze J, Boz C, Valanciute A, Burgess M, Emanuel P, Mills B, Rinaldi G, Hardisty G, Mills R, Findlay EG, Jabbal S, Duncan A, Plant S, Marshal ADL, Young I, Russell K, Scholefield E, Nimmo AF, Nazarov IB, Churchill GC, McCullagh JSO, Ebrahimi KH, Ferrett C, Templeton K, Rannard S, Owen A, Moore A, Finlayson K, Shankar-Hari M, Norrie J, Parker RA, Akram AR, Anthony DC, Dear JW, Hirani N, Dhaliwal K. | PubMed

 

A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies (2022).

Scott J, Mendive Tapia L, Gordon D, Barth N, Thompson E, Cheng Z, Taggart D, Kitamura T, Blas A B, Roberts E W, Juarez Jimenez J, Michel J, Piet B, de Vries I J, Verdoes M, Dawson J C, Carragher N O, O’Connor R A, Akram A R, Serrels A. Frame M C, Vendrell M. | PubMed

 

Fibroblast Activation Protein specific optical imaging in Non-Small Cell Lung Cancer (2022).

Mathieson L, O’Connor R A, Stewart H, Shaw P, Dhaliwal K, Williams G, Megia-Fernandez A, Akram A R. | PubMed

 

Understanding patient barriers and facilitators to uptake of lung screening using low dose computed tomography: a mixed methods scoping review of the current literature (2022).

Cavers D, Nelson M, Rostron J, Robb K A, Brown, L R, Campbell C, Akram A R, Dickie G, Mackean M, van Beek E J R, Sullivan F, Steele R J, Neilson A R, Weller D. | PubMed

 

Optimizing the implementation of lung cancer screening in Scotland: Focus group participant perspectives in the LUNGSCOT study (2022).

Cavers D, Nelson M, Rostron J, Robb K A, Brown L R, Campbell C, Akram A R, Dickie G, Mackean M, van Beek E J R, Sullivan F, Steele R J, Neilson A R, Weller D. | PubMed

 

Diagnosing ventilator-associated pneumonia (VAP) in UK NHS ICUs: the perceived value and role of a novel optical technology (2022).

Jones W S, Suklan J, Winter A, Green, K, Craven T, Bruce A, Mair J, Dhaliwal K, Walsh T, Simpson A J, Graziadio S, Allen A J. | PubMed

 

Fast and robust single-exponential decay recovery from noisy fluorescence lifetime imaging (2022).

Taimori A, Humphries D, Williams G, Dhaliwal K, Finlayson N, Hopgood J R. | PubMed

 

Phototherapeutic Induction of Immunogenic Cell Death and CD8+ T Cell-Granzyme B Mediated Cytolysis in Human Lung Cancer Cells and Organoids (2022).

Valančiūtė A, Mathieson L, O’Connor R A, Scott J I, Vendrell M, Dorward D A, Akram A R, Dhaliwal K. | PubMed

 

Deep Learning-Assisted Co-registration of Full-Spectral Autofluorescence Lifetime Microscopic Images with H&E-Stained Histology Images (2022).

Wang Q, Fernandes S, Williams G, Finlayson N, Akram A R, Dhaliwal K, Hopgood J R, Vallejo M. | PubMed

 

Design and Modelling of a Continuum Robot for Distal Lung Sampling in Mechanically Ventilated Patients in Critical Care: Frontiers in Robotics and AI (2021).

Mitros Z, Thamo B, Bergeles C, Da Cruz L, Dhaliwal K, Khadem M.| PubMed

 

Activated neutrophil fluorescent imaging technique for human lungs (2021).

Craven TH, Walton T, Akram AR, Scholefield E, McDonald N, Marshall AD, Humphries DC, Mills B, Campbell TA, Bruce A. | PubMed

 

Full spectrum fluorescence lifetime imaging with 0.5 nm spectral and 50 ps temporal resolution (2021)

Williams GOS, Williams E, Finlayson N, Erdogan AT, Wang Q, Fernandes S, Akram AR, Dhaliwal K, Henderson RK, Girkin JM, Bradley M. | PubMed

 

Sub millimetre flexible fibre probe for background and fluorescence free Raman spectroscopy (2021).

Yerolatsitis S, Kufcsák A, Ehrlich K, Wood HA, Fernandes S, Quinn T, Young V, Young I, Hamilton K, Akram AR. | PubMed 

 

Solitary pulmonary nodule imaging approaches and the role of optical fibre-based technologies (2021). Fernandes S, Williams G, Williams E, Ehrlich K, Stone J, Finlayson N, Bradley M, Thomson RR, Akram AR, Dhaliwal K. | PubMed

 

Multi-Scale Aggregated-Dilation Network for ex-vivo Lung Cancer Detection with Fluorescence Lifetime Imaging Endomicroscopy (2021).

Wang Q, Hopgood J R, Vallejo M. | PubMed

 

Tissue proteomic analysis identifies mechanisms and stages of immunopathology in fatal COVID-19 (2021)

Russell C D, Valanciute A, Gachanja N, Stephen J, Penrice-Randal R, Armstrong S D, Clohisey S, Wang B, Al Qsous W, Wallace W, Oniscu G, Stevens J, Harrison D J, Dhaliwal K, Hiscox J A, Baillie J K, Akram A R, David D, Lucas C D. | PubMed

 

T cells drive negative feedback mechanisms in Cancer Associated Fibroblasts, promoting expression of co-inhibitory ligands, CD73 and IL-27 in non-small cell lung cancer (2021)

O’Connor R A, Chauhan V, Mathieson L, Titmarsh H, Koppensteiner L, Young I, Tagliavini G, Dorward D, Prost S, Dhaliwal K, Wallace W, Akram A R. | PubMed

 

Activated neutrophil fluorescent imaging technique for human lungs (2021).

Craven T H, Walton T, Akram A R, Scholefield E, Mcdonald N, Marshall A D L, Humphries D C, Mills B, Campbell T A, Bruce A, Mair J, Dear J W, Newby D E, Hill A T, Walsh T S, Haslett C, Dhaliwal K. | PubMed

 

Deep Learning in ex-vivo Lung Cancer Discrimination using Fluorescence Lifetime Endomicroscopic Images (2020).

Wang Q, Hopgood JR, Finlayson N, Williams GO, Fernandes S, Williams E, Akram A, Dhaliwal K, Vallejo M.| PubMed

 

Molecular detection of Gram-positive bacteria in the human lung through an optical fiber–based endoscope (2020).

Mills B, Megia-Fernandez A, Norberg D, Duncan S, Marshall A, Akram AR, Quinn T, Young I, Bruce AM, Scholefield E. | PubMed

  

The role of fungi in fungal keratitis (2020)

Mills B, Radhakrishnan N, Karthikeyan Rajapandian SG, Rameshkumar G, Lalitha P, Prajna NV. | PubMed

 

Frugal filtering optical lenses for point-of-care diagnostics (2020)

Long J, Parker HE, Ehrlich K, Tanner MG, Dhaliwal K, Mills B. | PubMed

 

Time-Resolved Spectroscopy of Fluorescence Quenching in Optical Fibre-Based pH Sensors (2020)

Ehrlich K, Choudhary TR, Ucuncu M, Megia-Fernandez A, Harrington K, Wood HAC, Yu F, Choudhury D, Dhaliwal K, Bradley M, Tanner MG. | PubMed  

 

Polymyxin-based photosensitizer for the potent and selective killing of Gram-negative bacteria (2020).

Ucuncu M, Mills B, Duncan S, Staderini M, Dhaliwal K, Bradley M. | PubMed

 

Exploratory use of fluorescent SmartProbes for the rapid detection of microbial isolates causing corneal ulcer (2020).

Mills B, Megia-Fernandez A, Bradley M, Dhaliwal K, Williams R, Gunasekaran R, Lalitha P, Prajna NV. | PubMed 

 

Molecular detection of Gram-positive bacteria in the human lung through an optical fiber–based endoscope (2020).

Mills B, Megia-Fernandez A, Norberg D, Duncan S, Marshall A, Akram AR, Quinn T, Young I, Bruce AM, Scholefield E, Williams GOS, Krstajić N, Choudhary TR, Parker HE, Tanner MG, Harrington K, Wood HAC, Birks TA, Knight JC, Haslett C, Birks TA, Knight JC, Haslett C, Dhaliwal K, Bradley M, Ucuncu M, Stone JM. | PubMed 

 

A matrix metalloproteinase activation probe for painting human tumours (2020).

Mills B, Norberg D, Dhaliwal K, Akram AR, Bradley M, Megia-Fernandez A. | PubMed

 

Ultrafast-laser-ablation-assisted spatially selective attachment of fluorescent sensors onto optical fibers (2020)

Kamaljith V, Tanner MG, Wood HAC, Harrington K, Choudhury D, Bradley M, Thomson RR. | PubMed   

 

Genetic variation and potential for genetic improvement of cuticle deposition on chicken eggs (2019).

Dunn I, Woolliams J, Wilson P, Icken W, Cavero D, Jones A, Quinlan-Pluck F, Williams G, Olori V, Bain, M M. | PubMed

 

Enhanced avidity from a multivalent fluorescent antimicrobial peptide enables pathogen detection in a human lung model (2019).

Akram AR, Avlonitis N, Scholefield E, Vendrell M, McDonald N, Aslam T, Craven TH, Gray C, Collie DS, Fisher AJ. | PubMed

 

In situ identification of Gram-negative bacteria in human lungs using a topical fluorescent peptide targeting lipid A (2018).

Akram AR, Chankeshwara SV, Scholefield E, Aslam T, McDonald N, Megia-Fernandez A, Marshall A, Mills B, Avlonitis N, Craven TH, Smyth AM, Collie DS, Gray C, Hirani N, Hill AT, Govan JR, Walsh T, Haslett C, Bradley M, Dhaliwal K. | PubMed

 

Early arriving photon imaging for locating optical endomicroscopy fibres and medical devices (2018).

Tanner M G, Choudhary T, Craven T, Mills B, Bradley M, Henderson R, Dhaliwal K, Thomson RR. | PubMed

 

Bimodal fluorogenic sensing of matrix proteolytic signatures in lung cancer (2018).

Megia-fernandez A, Mills B, Michels C, Chankeshwara, S V, Krstajić N, Haslett C, Dhaliwal K, Bradley M.  | PubMed

 

Low-cost high sensitivity pulsed endomicroscopy to visualize tricolor optical signatures (2018)

Krstajić N, Mills B, Murray I, Marshall A, Norberg D, Craven TH, Emanuel P, Choudhary TR, Williams GOS, Scholefield E, Akram AR, Davie A, Hirani N, Bruce A, Moore A, Bradley M, Dhaliwal K. | PubMed 

  

Development of an Alveolar Transbronchial Catheter for Concurrent Fiber Optics-Based Imaging and Fluid Delivery (2018).

Knighton N, Cottle B, Dentan V, Vercauteren T, Akram A, Bruce A, Dhaliwal K, Hitchcock R.| PubMed

 

Super-silent FRET sensor enables live cell imaging and flow cytometric stratification of intracellular serine protease activity in neutrophils (2018).

Craven TH, Avlonitis N, McDonald N, Walton T, Scholefield E, Akram AR, Walsh TS, Haslett C, Bradley M, Dhaliwal K. | PubMed 

 

In situ identification of Gram-negative bacteria in human lungs using a topical fluorescent peptide targeting lipid A (2018).

Akram AR, Chankeshwara SV, Scholefield E, Aslam T, McDonald N, Megia-Fernandez A, Marshall A, Mills B, Avlonitis N, Craven TH. | PubMed

 

pH sensing through a single optical fibre using SERS and CMOS SPAD line arrays (2017)

K Ehrlich, A Kufcsák, S McAughtrie, H Fleming, N Krstajic, C J Campbell, R K Henderson, K Dhaliwal, R R Thomson, M G Tanner. | PubMed

 

Highly selective and rapidly activatable fluorogenic Thrombin sensors and application in human lung tissue (2017)

Megia-fernandez A, Mills B, Michels C, Chankeshwara SV, Dhaliwal K, Bradley M. | PubMed

 

Ballistic and snake photon imaging for locating optical endomicroscopy fibres (2017).

Tanner MG, Choudhary TR, Craven TH, Mills B, Bradley M, Henderson RK, Dhaliwal K, Thomson, RR. | PubMed

 

Optical Screening of Novel Bacteria-specific Probes on Ex Vivo Human Lung Tissue by Confocal Laser Endomicroscopy (2017).

Mills B, Akram AUH, Scholefield E, Bradley M, Dhaliwal K. | PubMed

 

Time-resolved spectroscopy at 19,000 lines per second using a CMOS SPAD line array enables advanced biophotonics applications (2017).

A Kufcsák, A Erdogan, R Walker, K Ehrlich, M Tanner, A Megia-Fernandez, E Scholefield, P Emanuel, K Dhaliwal, M Bradley, R K Henderson, N Krstajić. | PubMed

 

Assessing the utility of autofluorescence-based pulmonary optical endomicroscopy to predict the malignant potential of solitary pulmonary nodules in humans (2016).

Seth S, Akram AR, McCool P, Westerfeld J, Wilson D, McLaughlin S, Dhaliwal K, Williams CK.| PubMed

 

Two-color widefield fluorescence microendoscopy enables multiplexed molecular imaging in the alveolar space of human lung tissue (2016).

Krstajić N, Akram AR, Choudhary TR, McDonald N, Tanner MG, Pedretti E, Dalgarno PA, Scholefield E, Girkin JM, Moore A. | PubMed

 

Endoscopic sensing of alveolar pH (2016).

Choudhury D, Tanner MG, McAughtrie S, Yu F, Mills B, Choudhary TR, Seth S, Craven TH, Stone JM, Mati IK, Campbell CJ , Bradley M, Williams CKI, Dhaliwal K, Birks TA, Thomson RR. | PubMed

 

 

Optical molecular imaging of lysyl oxidase activity–detection of active fibrogenesis in human lung tissue (2015).

Aslam T, Miele A, Chankeshwara SV, Megia-Fernandez A, Michels C, Akram AR, McDonald N, Hirani N, Haslett C, Bradley M.| PubMed

 

A labelled-ubiquicidin antimicrobial peptide for immediate in situ optical detection of live bacteria in human alveolar lung tissue (2015).

Akram AR, Avlonitis N, Lilienkampf A, Perez-Lopez AM, McDonald N, Chankeshwara SV, Scholefield E, Haslett C, Bradley M, Dhaliwal K. | PubMed

 

Publications

 

Computational Fluorescence Suppression in Shifted Excitation Raman Spectroscopy (2023).
Jenkins N, Ehrlich K, Kufcsak A, Yerolatsitis S, Fernandes S, Young I, Hamilton K, Wood HA, Quinn T, Young V, Akram AR, Stone JM, Thomson RR, Finlayson K, Dhaliwal K, Seth S. | PubMed 

 

Simultaneous Spectral Temporal Modelling for a Time-Resolved Fluorescence Emission Spectrum (2023)
Adams AC, Kufcsak A, Ehrlich K, Dhaliwal K, Seth S. | PubMed 

 

Tri-mode optical biopsy probe with fluorescence endomicroscopy, Raman spectroscopy, and time-resolved fluorescence spectroscopy (2022). 

Wood HA, Ehrlich K, Yerolatsitis S, Kufcsák A, Quinn TM, Fernandes S, Norberg D, Jenkins NC, Young V, Young I, Hamilton K, Seth S, Akram AR,Thomson RR, Finlayson K, Dhaliwal K, Stone JM. | PubMed

 

High resolution TCSPC imaging of diffuse light with a one-dimensional SPAD array scanning system (2022).

E P McShane, H K Chandrasekharan, A Kufcsák, N Finlayson, A T Erdogan, R K Henderson, K Dhaliwal, R R Thomson, M G Tanner | PubMed 

 

An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis (DEFINE): A Phase Ib/IIa Randomised Controlled Trial (2022).

Gaughan EE, Quinn TM, Mills A, Bruce A M, Antonelli J, Mackinnon A, Aslanis V, Li F, O’connor R, Boz C, Mills R, Emanuel P, Burgess M, Rinaldi G, Valanciute A, Mills B, Scholefield E, Hardisty G, Gwyer Findlay E, Parker R A, Norrie J, Dear JW, Akram AR, Koch O, Templeton K, Dockrell DH, Walsh TS, Partridge S, Humphries D, Wang-Jairaj J, Slack RJ, Schambye H, Phung D, Gravelle L, Lindmark B, Shankar-Hari M, Hirani N, Sethi T, Dhaliwal K. | PubMed

 

Randomised Controlled Trial of Intravenous Nafamostat Mesylate in COVID pneumonitis: Phase 1b/2a Experimental Study to Investigate Safety, Pharmacokinetics and Pharmacodynamics (2022).

Quinn T, Gaughan E E, Bruce A, Antonelli J, O’Connor R A, Li F, McNamara S, Koch O, Mackintosh C, Dockrell D, Walsh T, Blyth K G, Church C, Schwarze J, Boz C, Valanciute A, Burgess M, Emanuel P, Mills B, Rinaldi G, Hardisty G, Mills R, Findlay EG, Jabbal S, Duncan A, Plant S, Marshal ADL, Young I, Russell K, Scholefield E, Nimmo AF, Nazarov IB, Churchill GC, McCullagh JSO, Ebrahimi KH, Ferrett C, Templeton K, Rannard S, Owen A, Moore A, Finlayson K, Shankar-Hari M, Norrie J, Parker RA, Akram AR, Anthony DC, Dear JW, Hirani N, Dhaliwal K. | PubMed

 

A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies (2022).

Scott J, Mendive Tapia L, Gordon D, Barth N, Thompson E, Cheng Z, Taggart D, Kitamura T, Blas A B, Roberts E W, Juarez Jimenez J, Michel J, Piet B, de Vries I J, Verdoes M, Dawson J C, Carragher N O, O’Connor R A, Akram A R, Serrels A. Frame M C, Vendrell M. | PubMed

 

Fibroblast Activation Protein specific optical imaging in Non-Small Cell Lung Cancer (2022).

Mathieson L, O’Connor R A, Stewart H, Shaw P, Dhaliwal K, Williams G, Megia-Fernandez A, Akram A R. | PubMed

 

Understanding patient barriers and facilitators to uptake of lung screening using low dose computed tomography: a mixed methods scoping review of the current literature (2022).

Cavers D, Nelson M, Rostron J, Robb K A, Brown, L R, Campbell C, Akram A R, Dickie G, Mackean M, van Beek E J R, Sullivan F, Steele R J, Neilson A R, Weller D. | PubMed

 

Optimizing the implementation of lung cancer screening in Scotland: Focus group participant perspectives in the LUNGSCOT study (2022).

Cavers D, Nelson M, Rostron J, Robb K A, Brown L R, Campbell C, Akram A R, Dickie G, Mackean M, van Beek E J R, Sullivan F, Steele R J, Neilson A R, Weller D. | PubMed

 

Diagnosing ventilator-associated pneumonia (VAP) in UK NHS ICUs: the perceived value and role of a novel optical technology (2022).

Jones W S, Suklan J, Winter A, Green, K, Craven T, Bruce A, Mair J, Dhaliwal K, Walsh T, Simpson A J, Graziadio S, Allen A J. | PubMed

 

Fast and robust single-exponential decay recovery from noisy fluorescence lifetime imaging (2022).

Taimori A, Humphries D, Williams G, Dhaliwal K, Finlayson N, Hopgood J R. | PubMed

 

Phototherapeutic Induction of Immunogenic Cell Death and CD8+ T Cell-Granzyme B Mediated Cytolysis in Human Lung Cancer Cells and Organoids (2022).

Valančiūtė A, Mathieson L, O’Connor R A, Scott J I, Vendrell M, Dorward D A, Akram A R, Dhaliwal K. | PubMed

 

Deep Learning-Assisted Co-registration of Full-Spectral Autofluorescence Lifetime Microscopic Images with H&E-Stained Histology Images (2022).

Wang Q, Fernandes S, Williams G, Finlayson N, Akram A R, Dhaliwal K, Hopgood J R, Vallejo M. | PubMed

 

Design and Modelling of a Continuum Robot for Distal Lung Sampling in Mechanically Ventilated Patients in Critical Care: Frontiers in Robotics and AI (2021).

Mitros Z, Thamo B, Bergeles C, Da Cruz L, Dhaliwal K, Khadem M.| PubMed

 

Activated neutrophil fluorescent imaging technique for human lungs (2021).

Craven TH, Walton T, Akram AR, Scholefield E, McDonald N, Marshall AD, Humphries DC, Mills B, Campbell TA, Bruce A. | PubMed

 

Full spectrum fluorescence lifetime imaging with 0.5 nm spectral and 50 ps temporal resolution (2021)

Williams GOS, Williams E, Finlayson N, Erdogan AT, Wang Q, Fernandes S, Akram AR, Dhaliwal K, Henderson RK, Girkin JM, Bradley M. | PubMed

 

Sub millimetre flexible fibre probe for background and fluorescence free Raman spectroscopy (2021).

Yerolatsitis S, Kufcsák A, Ehrlich K, Wood HA, Fernandes S, Quinn T, Young V, Young I, Hamilton K, Akram AR. | PubMed 

 

Solitary pulmonary nodule imaging approaches and the role of optical fibre-based technologies (2021). Fernandes S, Williams G, Williams E, Ehrlich K, Stone J, Finlayson N, Bradley M, Thomson RR, Akram AR, Dhaliwal K. | PubMed

 

Multi-Scale Aggregated-Dilation Network for ex-vivo Lung Cancer Detection with Fluorescence Lifetime Imaging Endomicroscopy (2021).

Wang Q, Hopgood J R, Vallejo M. | PubMed

 

Tissue proteomic analysis identifies mechanisms and stages of immunopathology in fatal COVID-19 (2021)

Russell C D, Valanciute A, Gachanja N, Stephen J, Penrice-Randal R, Armstrong S D, Clohisey S, Wang B, Al Qsous W, Wallace W, Oniscu G, Stevens J, Harrison D J, Dhaliwal K, Hiscox J A, Baillie J K, Akram A R, David D, Lucas C D. | PubMed

 

T cells drive negative feedback mechanisms in Cancer Associated Fibroblasts, promoting expression of co-inhibitory ligands, CD73 and IL-27 in non-small cell lung cancer (2021)

O’Connor R A, Chauhan V, Mathieson L, Titmarsh H, Koppensteiner L, Young I, Tagliavini G, Dorward D, Prost S, Dhaliwal K, Wallace W, Akram A R. | PubMed

 

Activated neutrophil fluorescent imaging technique for human lungs (2021).

Craven T H, Walton T, Akram A R, Scholefield E, Mcdonald N, Marshall A D L, Humphries D C, Mills B, Campbell T A, Bruce A, Mair J, Dear J W, Newby D E, Hill A T, Walsh T S, Haslett C, Dhaliwal K. | PubMed

 

Deep Learning in ex-vivo Lung Cancer Discrimination using Fluorescence Lifetime Endomicroscopic Images (2020).

Wang Q, Hopgood JR, Finlayson N, Williams GO, Fernandes S, Williams E, Akram A, Dhaliwal K, Vallejo M.| PubMed

 

Molecular detection of Gram-positive bacteria in the human lung through an optical fiber–based endoscope (2020).

Mills B, Megia-Fernandez A, Norberg D, Duncan S, Marshall A, Akram AR, Quinn T, Young I, Bruce AM, Scholefield E. | PubMed

  

The role of fungi in fungal keratitis (2020)

Mills B, Radhakrishnan N, Karthikeyan Rajapandian SG, Rameshkumar G, Lalitha P, Prajna NV. | PubMed

 

Frugal filtering optical lenses for point-of-care diagnostics (2020)

Long J, Parker HE, Ehrlich K, Tanner MG, Dhaliwal K, Mills B. | PubMed

 

Time-Resolved Spectroscopy of Fluorescence Quenching in Optical Fibre-Based pH Sensors (2020)

Ehrlich K, Choudhary TR, Ucuncu M, Megia-Fernandez A, Harrington K, Wood HAC, Yu F, Choudhury D, Dhaliwal K, Bradley M, Tanner MG. | PubMed  

 

Polymyxin-based photosensitizer for the potent and selective killing of Gram-negative bacteria (2020).

Ucuncu M, Mills B, Duncan S, Staderini M, Dhaliwal K, Bradley M. | PubMed

 

Exploratory use of fluorescent SmartProbes for the rapid detection of microbial isolates causing corneal ulcer (2020).

Mills B, Megia-Fernandez A, Bradley M, Dhaliwal K, Williams R, Gunasekaran R, Lalitha P, Prajna NV. | PubMed 

 

Molecular detection of Gram-positive bacteria in the human lung through an optical fiber–based endoscope (2020).

Mills B, Megia-Fernandez A, Norberg D, Duncan S, Marshall A, Akram AR, Quinn T, Young I, Bruce AM, Scholefield E, Williams GOS, Krstajić N, Choudhary TR, Parker HE, Tanner MG, Harrington K, Wood HAC, Birks TA, Knight JC, Haslett C, Birks TA, Knight JC, Haslett C, Dhaliwal K, Bradley M, Ucuncu M, Stone JM. | PubMed 

 

A matrix metalloproteinase activation probe for painting human tumours (2020).

Mills B, Norberg D, Dhaliwal K, Akram AR, Bradley M, Megia-Fernandez A. | PubMed

 

Ultrafast-laser-ablation-assisted spatially selective attachment of fluorescent sensors onto optical fibers (2020)

Kamaljith V, Tanner MG, Wood HAC, Harrington K, Choudhury D, Bradley M, Thomson RR. | PubMed   

 

Genetic variation and potential for genetic improvement of cuticle deposition on chicken eggs (2019).

Dunn I, Woolliams J, Wilson P, Icken W, Cavero D, Jones A, Quinlan-Pluck F, Williams G, Olori V, Bain, M M. | PubMed

 

Enhanced avidity from a multivalent fluorescent antimicrobial peptide enables pathogen detection in a human lung model (2019).

Akram AR, Avlonitis N, Scholefield E, Vendrell M, McDonald N, Aslam T, Craven TH, Gray C, Collie DS, Fisher AJ. | PubMed

 

In situ identification of Gram-negative bacteria in human lungs using a topical fluorescent peptide targeting lipid A (2018).

Akram AR, Chankeshwara SV, Scholefield E, Aslam T, McDonald N, Megia-Fernandez A, Marshall A, Mills B, Avlonitis N, Craven TH, Smyth AM, Collie DS, Gray C, Hirani N, Hill AT, Govan JR, Walsh T, Haslett C, Bradley M, Dhaliwal K. | PubMed

 

Early arriving photon imaging for locating optical endomicroscopy fibres and medical devices (2018).

Tanner M G, Choudhary T, Craven T, Mills B, Bradley M, Henderson R, Dhaliwal K, Thomson RR. | PubMed

 

Bimodal fluorogenic sensing of matrix proteolytic signatures in lung cancer (2018).

Megia-fernandez A, Mills B, Michels C, Chankeshwara, S V, Krstajić N, Haslett C, Dhaliwal K, Bradley M.  | PubMed

 

Low-cost high sensitivity pulsed endomicroscopy to visualize tricolor optical signatures (2018)

Krstajić N, Mills B, Murray I, Marshall A, Norberg D, Craven TH, Emanuel P, Choudhary TR, Williams GOS, Scholefield E, Akram AR, Davie A, Hirani N, Bruce A, Moore A, Bradley M, Dhaliwal K. | PubMed 

  

Development of an Alveolar Transbronchial Catheter for Concurrent Fiber Optics-Based Imaging and Fluid Delivery (2018).

Knighton N, Cottle B, Dentan V, Vercauteren T, Akram A, Bruce A, Dhaliwal K, Hitchcock R.| PubMed

 

Super-silent FRET sensor enables live cell imaging and flow cytometric stratification of intracellular serine protease activity in neutrophils (2018).

Craven TH, Avlonitis N, McDonald N, Walton T, Scholefield E, Akram AR, Walsh TS, Haslett C, Bradley M, Dhaliwal K. | PubMed 

 

In situ identification of Gram-negative bacteria in human lungs using a topical fluorescent peptide targeting lipid A (2018).

Akram AR, Chankeshwara SV, Scholefield E, Aslam T, McDonald N, Megia-Fernandez A, Marshall A, Mills B, Avlonitis N, Craven TH. | PubMed

 

pH sensing through a single optical fibre using SERS and CMOS SPAD line arrays (2017)

K Ehrlich, A Kufcsák, S McAughtrie, H Fleming, N Krstajic, C J Campbell, R K Henderson, K Dhaliwal, R R Thomson, M G Tanner. | PubMed

 

Highly selective and rapidly activatable fluorogenic Thrombin sensors and application in human lung tissue (2017)

Megia-fernandez A, Mills B, Michels C, Chankeshwara SV, Dhaliwal K, Bradley M. | PubMed

 

Ballistic and snake photon imaging for locating optical endomicroscopy fibres (2017).

Tanner MG, Choudhary TR, Craven TH, Mills B, Bradley M, Henderson RK, Dhaliwal K, Thomson, RR. | PubMed

 

Optical Screening of Novel Bacteria-specific Probes on Ex Vivo Human Lung Tissue by Confocal Laser Endomicroscopy (2017).

Mills B, Akram AUH, Scholefield E, Bradley M, Dhaliwal K. | PubMed

 

Time-resolved spectroscopy at 19,000 lines per second using a CMOS SPAD line array enables advanced biophotonics applications (2017).

A Kufcsák, A Erdogan, R Walker, K Ehrlich, M Tanner, A Megia-Fernandez, E Scholefield, P Emanuel, K Dhaliwal, M Bradley, R K Henderson, N Krstajić. | PubMed

 

Assessing the utility of autofluorescence-based pulmonary optical endomicroscopy to predict the malignant potential of solitary pulmonary nodules in humans (2016).

Seth S, Akram AR, McCool P, Westerfeld J, Wilson D, McLaughlin S, Dhaliwal K, Williams CK.| PubMed

 

Two-color widefield fluorescence microendoscopy enables multiplexed molecular imaging in the alveolar space of human lung tissue (2016).

Krstajić N, Akram AR, Choudhary TR, McDonald N, Tanner MG, Pedretti E, Dalgarno PA, Scholefield E, Girkin JM, Moore A. | PubMed

 

Endoscopic sensing of alveolar pH (2016).

Choudhury D, Tanner MG, McAughtrie S, Yu F, Mills B, Choudhary TR, Seth S, Craven TH, Stone JM, Mati IK, Campbell CJ , Bradley M, Williams CKI, Dhaliwal K, Birks TA, Thomson RR. | PubMed

 

 

Optical molecular imaging of lysyl oxidase activity–detection of active fibrogenesis in human lung tissue (2015).

Aslam T, Miele A, Chankeshwara SV, Megia-Fernandez A, Michels C, Akram AR, McDonald N, Hirani N, Haslett C, Bradley M.| PubMed

 

A labelled-ubiquicidin antimicrobial peptide for immediate in situ optical detection of live bacteria in human alveolar lung tissue (2015).

Akram AR, Avlonitis N, Lilienkampf A, Perez-Lopez AM, McDonald N, Chankeshwara SV, Scholefield E, Haslett C, Bradley M, Dhaliwal K. | PubMed

 

Specific in situ immuno-imaging of pulmonary-resident memory lymphocytes in human lungs (2023)

Simultaneous Spectral Temporal Modelling for a Time-Resolved Fluorescence Emission Spectrum (2023)

A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies (2022)

An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis (DEFINE): A Phase Ib/IIa Randomised Controlled Trial (2022)

Deep Learning-Assisted Co-registration of Full-Spectral Autofluorescence Lifetime Microscopic Images with H&E-Stained Histology Images (2022)

Diagnosing ventilator-associated pneumonia (VAP) in UK NHS ICUs: the perceived value and role of a novel optical technology (2022)

Fast and robust single-exponential decay recovery from noisy fluorescence lifetime imaging (2022)

Fibroblast Activation Protein specific optical imaging in Non-Small Cell Lung Cancer (2022).

High resolution TCSPC imaging of diffuse light with a one-dimensional SPAD array scanning system (2022).

Optimizing the implementation of lung cancer screening in Scotland: Focus group participant perspectives in the LUNGSCOT study (2022).

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